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DynaPro ZetaStar™ Dynamic, Electrophoretic, and Static Light Scattering Detector

Waters | Wyatt TechnologyAvailable: Worldwide

Unique among its peers, the DynaPro ZetaStar™ performs simultaneous dynamic and static light scattering or dynamic and electrophoretic light scattering (DLS/SLS/ELS) measurements all within one instrument. Measure manually with microcuvettes, or automatically via an autosampler and flow cell. Quickly assess size, polydispersity, zeta potential, charge, particle concentration, molar mass or turbidity for characterization and st…

Waters | Wyatt Technology

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Description

Unique among its peers, the DynaPro ZetaStar™ performs simultaneous dynamic and static light scattering or dynamic and electrophoretic light scattering (DLS/SLS/ELS) measurements all within one instrument. Measure manually with microcuvettes, or automatically via an autosampler and flow cell. Quickly assess size, polydispersity, zeta potential, charge, particle concentration, molar mass or turbidity for characterization and stability studies.

Key Features:

  • DYNAMICS Touch on-board app for walk-up, self-guided operation
  • Adaptive collection for faster and simpler measurements of zeta potential
  • Measure size and turbidity with just 2 µL of solution, or zeta potential with as little as 65 µL of solution
  • Measure zeta potential in buffers with conductivity up to 2x physiological saline
  • A selection of high-quality quartz and disposable cells and cuvettes for both size and zeta potential measurements.

A biopharmaceutical workflow powered by Wyatt Technology

Reliable biophysical characterization is a cornerstone of biologics development, playing a critical role at every stage – from selecting promising drug candidates to optimizing formulations and ensuring consistent manufacturing processes. Explore a comprehensive guide on how to deliver biopharmaceutical solutions, beginning with light scattering technology.


Application NoteLife Sciences

Particle size analysis by DLS for optimization of protein complexes for measurement by small-angle neutron scattering

Explore how dynamic light scattering (DLS) can be used to ensure monodispersity in protein samples for small-angle neutron scattering (SANS) studies. Discover how researchers using the DynaPro™ Plate Reader, detected protein aggregation that was undetectable by SDS-PAGE and UV spectroscopy. This method enhances sample quality assessment, ensuring reliable SANS measurements for studying Type I bacterial restriction-modification systems.


Application NoteLife Sciences

Measuring size, concentration, and zeta potential of LNPs with the DynaPro ZetaStar

Microfluidic formulation of RNA-containing lipid nanoparticles (LNP-RNA) is a common means of developing and producing this important non-viral modality of gene delivery. A key challenge during formulation is the selection of the specific lipids and formulation conditions to achieve the desired particle sizes and surface potential. Discover how by using the DynaPro™ ZetaStar™ instrument, researchers can rapidly characterize size, polydispersity, and zeta potential, comparing outcomes from two LNP formulation techniques to optimize efficiency and performance.

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