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Trending in microbiome: From comprehensive culture workflows, to novel biotherapeutics, and microbial characterization

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Discover the latest technologies and techniques that are revolutionizing microbiome research

2 Sept 2019
Charlie Carter
Life Sciences Editor

Editorial article

In recent years, research into the human microbiome, our personal communities of diverse microorganisms, has thrived. However, when it comes to the true importance of these microbes, there is still a lot to be uncovered. In this article, we cover the latest advancements in microbiome research, from the development of biotherapeutics to counter inflammatory bowel disease, to groundbreaking discoveries in the world of gut microbes. Plus, find out how Eppendorf’s bioprocessing systems can help support your microbiome research.

Standardizing microbiome research: culture from discovery to production

Find out more about Eppendorf’s microbiome culture workflow, including information on the diverse culturing needs of gut microbes and the scalable bioprocess systems that are available for culture research to production.

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Creating novel microbial technology for gut biotherapeutics

Don Whitley Scientific A25 Anaerobic Workstation
Don Whitley Scientific A25 Anaerobic Workstation

Find out how anaerobic workstations from Don Whitley Scientific are being used to develop novel Clostridium-assisted drug delivery platforms for biotherapeutics to counter inflammatory bowel disease.

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Efficient ribosomal RNA depletion against any species for RNA-seq

Discover siTOOLs’ method for designing, producing, and testing the performance of rRNA depletion probes (riboPOOL) against the current commercial solution for human and mouse total RNA samples.

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Host DNA depletion for deeper microbiome and metagenome analysis

SelectNA™plus robot for MolYsis-SelectNA™plus
SelectNA™plus robot for MolYsis by Molzym GmbH & Co. KG

In many samples, host DNA greatly outnumbers microbial DNA. Discover how MolYsis™ technology from Molzym is designed for the depletion of host DNA before extraction of microbial DNA to increase the power of resolution of microbial structures.

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High-throughput microbiome characterization

Watch Mike Humphrys describe a novel automated workflow for 16S rRNA sequencing using the mosquito HV genomics liquid handling platform from TTP Labtech. This method promises dramatically reduced hands-on time and reagent consumption with miniaturized reaction volumes.

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Related Microbiome Resources:

  • The Diet Bacteria: Why we are what our microbes eat - Pioneering microbiome scientist Prof. Patrice Cani reveals how his work has unearthed some of the most groundbreaking discoveries in the world of gut microbes, and how they influence human physiology. Read full interview>>

  • How to buy microscopy equipment - If you are looking to invest in a microscope, this essential guide provides you with all the information you need to make the right purchasing decisions. Learn about key factors and application considerations for your imaging needs. Plus, read reviews from your peers to help you buy with confidence. Download free eBook>>

  • Latest reviews - Read reviews left by other microbiome scientists to help you choose the best instruments for your lab or share your opinion to help your peers by writing your own review today. Read one of our latest reviews below by Kerrie Davies from the University of Leeds about the Whitley A95 Anaerobic Workstation by Don Whitley Scientific:
5 star review of the Whitley A95 Anaerobic Workstation by Don Whitley Scientific

Visit our microbiome special feature for more of the latest>>

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MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA / RNA QuantificationDetection and quantification of nucleic acids is important in molecular biology, cloning, expression, forensics and clinical diagnostics. Nucleic acids can be detected by labeling with colorimetric, fluorescent or radio labels and using in situ hybridization kits to identify specific sequences. Multiple nucleic acids can be detected and quantified at once using RNA / DNA detection beads or RNA / DNA microarrays. Find the best DNA / RNA Quantification products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNADeoxyribonucleic Acid (DNA) is the main component of chromosomes and the carrier of genetic information of living organisms. Find out here about PCR, NGS, ChIP-Seq, gel imaging, and many other techniques which can be used for the analysis of DNA.High ThroughputHigh throughput experiments allow the simultaneous processing of several samples. This parallelization reduces the cost per experiment and increases reproducibility and output volume of data.RNARNA is a nucleic acid that plays a key role in gene expression and protein synthesis. It serves as a messenger between DNA and ribosomes, carrying genetic instructions to produce proteins. Advances in RNA-based therapies, such as mRNA vaccines and gene editing, have revolutionized treatment strategies for genetic disorders and infectious diseases. Explore RNA research tools and therapies in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.SequencingSequencing refers to determining the order of nucleotides in a DNA or RNA molecule. This process is essential in genomics, diagnostics, and evolutionary biology. Techniques like next-generation sequencing (NGS) and Sanger sequencing provide high-throughput and precise data for analyzing genomes and transcriptomes. Browse our peer-reviewed product directory to find the best sequencing tools and reagents, compare products, check reviews, and get pricing directly from manufacturers.BiotherapeuticsBiotherapeutics are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or in <i>in vivo</i> diagnostics. The most well-known example of a biotherapeutic product, and the first to be approved for therapeutic use, was recombinant human insulin.MicrobiomeMicrobiome research focuses on the complex communities of microorganisms living in and on humans, animals, plants, and environments. It plays a crucial role in health, disease, and ecological balance. Explore tools and resources for microbiome analysis, including sequencing platforms and bioinformatics software.Liquid HandlingLiquid handling involves the precise transfer, mixing, and dispensing of liquids in laboratory settings. It is essential for accurate and consistent results in biological, chemical, and pharmaceutical research. Automated liquid handling systems improve efficiency and reduce human error in sample preparation and analysis. Explore liquid handling tools in our peer-reviewed product directory; compare products, read customer reviews, and get pricing directly from manufacturers.

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