riboPOOL
riboPOOL by siTOOLs Biotech is the market‘s most flexible solution in ribosomal RNA (rRNA) depletion prior to RNA-Seq or other analysis. Achieve efficient and specific rRNA depletion for any species with siTOOL’s proprietary oligo design and high complexity pooling technology. Suitable for metagenomic RNA-Seq and non-polyA-dependent.
Pan-Prokaryote riboPOOL
How it works: rRNA Depletion Workflow
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Detection of scientifically relevant RNAs by Next-Generation RNA Sequencing (RNA-Seq) is greatly limited by highly abundant ribosomal RNAs (rRNAs) which occupy > 90% RNA-Seq reads. Current rRNA depletion solutions however are often costly and limited to well-studied species.
Ribosomal RNA depletion pools (riboPOOLs) by siTOOLs Biotech is the market's most flexible solution in rRNA depletion. With a diverse selection of Ready-Made riboPOOLs and the ability to create your own Custom riboPOOL, riboPOOLs are ideal for sequencing experts with custom demands and scientists working on rare species.
Composed of high complexity pools of optimally-designed biotinylated DNA probes, riboPOOLs are highly efficient, even outperforming Ribo-Zero (Illumina), depleting ~10% more rRNA while leaving other RNA intact.
For microbiologists, the new Pan-Prokaryote riboPOOL provides universal rRNA depletion for a wide spectrum of microbes and is suited for metagenomic or microbiome samples. Combination riboPOOLs are also available to deplete rRNAs from samples containing multiple species.
