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Thermo Fisher Scientific Introduces Kit to Simplify Detection and Analysis of Hormones in Water

Thermo Fisher Scientific
29 Oct 2012

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Thermo Fisher Scientific Inc., the world leader in serving science, has introduced the Thermo Scientific Hormones Application Kit, a complete package designed to simplify the detection and analysis of hormone contaminants in ground water and drinking water samples using liquid chromatography/tandem mass spectrometry (LC-MS/MS).

This application kit is designed to streamline and accelerate sample preparation, handling and analysis using a verified protocol for EPA Method 539, “Determination of Hormones in Drinking Water by Solid Phase Extraction (SPE) and Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry (LC-ESI-MS/MS).” Thermo Fisher application chemists experienced substantial productivity gains using the new kits to comply with EPA Unregulated Contaminant Monitoring Rule 3, where public water systems are monitored for 30 contaminants. The Hormones Application Kit is designed for use with the Thermo Scientific TSQ series triple quadrupole LC-MS/MS system with UltiMate 3000 series LC.

“We developed these kits to reduce a major pain point for chemists -- time-consuming and costly method development,” said Dipankar Ghosh, Thermo Fisher marketing director, environment and food safety. “Many of our customers are looking at multiple residues from different classes of compounds, and method development is often very challenging.”

In recent years, pharmaceutical compounds and estrogen have been detected in environmental water and drinking water in many locations around the world, according to an Associated Press investigation of drinking water in 24 major U.S metropolitan areas and numerous other studies. The effects of these highly active compounds on wildlife and humans have been a concern to a wide range of environmental scientists and biologists.

The starter Thermo Scientific Hormones Application Kit contains a Thermo Scientific Accucore HPLC column, solid phase extraction disks, MS-Certified vials, a detailed application protocol and Thermo Scientific TraceFinder software method files, which can be uploaded into the instrument software. Customers can purchase the kit bundled with a Thermo Scientific LC-MS/MS system, or as a standalone item.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Environmental Monitoring and TestingEnvironmental monitoring and testing uses handheld portable analyzers, kits, spectrometers or chromatography systems for air, water, soil, food and other sample testing. Useful features of analyzers such as BOD and COD include portability, easy calibration, automation and sensitivity.  Environmental test kits for pH, water, moisture, etc, should be accurate, sensitive, reliable, fast and easy to use.Solid-Phase ExtractionSolid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Food and Beverage AnalyzersFood and Beverage Analyzers are commonly used to provide information about the chemical composition, structure and physical properties of food materials.HormonesWater AnalysisAnalytical methods used to test the purity of drinking water include determining the level of contaminants abides to the level set by the Environmental Protection Agency (EPA).Drinking Water AnalysisAnalytical methods used to test the purity of drinking water include determining the level of contaminants abides to the level set by the Environmental Protection Agency (EPA).Contamination PreventionContamination prevention aims to control and minimize the risk of contamination during experiments. Biological safety cabinets and sterilization equipment are examples of technologies used to prevent contamination.EPA MethodsEPA methods are procedures approved by the U.S. Environmental Protection Agency for monitoring and analyzing environmental pollutants, including air, water, and soil samples. These methods are critical in ensuring public health and environmental safety. Explore EPA methods and tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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Thermo Fisher Scientific Introduces Kit to Simplify Detection and Analysis of Hormones in Water