Shimadzu launches new ion chromatograph with built-in electrodialytic suppressor

Proving that the best thing comes in small packages, the compact chromatograph aims to deliver reliable performance

4 Jun 2020
Diane Li
Assistant Editor

Product news

Shimadzu, one of the world leaders in analytical instrumentation, has introduced the new HIC-ESP (Ion Chromatograph) featuring a built-in electrodialytic suppressor. This outstanding anion suppressor minimizes band spreading and achieves high sensitivity and reliable performance for the quantitative determination of anions. The suppressor is rugged, providing stable functionality over long periods of operation. Furthermore, the system’s small footprint requires less bench space in usually densely-packed laboratories: Best things come in small packages. The HIC-ESP covers a wide range of applications in environmental testing, pharma, chemistry and food science.

The HIC-ESP modular inert flow path system integrates a system controller, degasser, pump, CDD detector with temperature controlled flow cell, autosampler, slim-line oven and the anion suppressor. This new ion chromatography system combines a number of valuable features providing highly-reliable analytical results: Excellent solvent delivery performance, low carryover, fast injection speed (as low as 10 sec), high sample injection precision and repeatability, precise oven temperature regulation and more.

High efficiency and stability

The new ICDS-40A anion suppressor is located between the IC column and the detector. The unit features a low-volume design combined with a unique multi-layered structure. With a folded membrane, it provides highly efficient electrodialytic background suppression and increased stability. The patent-pending design reduces peak spreading, increasing sensitivity for components with low retention such as fluoride, and improves separation from the water dip.

The ICDS-40A allows for analysis as well as self-regeneration simultaneously, shortening analysis cycle time and maximizing workflow efficiency. Because the anion suppressor uses effluent from the detector as regenerant, it eliminates the need for cumbersome offline regeneration with environmentally unfriendly solutions such as sulfuric acid.

Seamless integration with software platform

In addition, the user-friendly ion chromatography system integrates seamlessly with Shimadzu’s LabSolutions platform. This allows users to easily manage parameter setting for IC analysis, batch analyses, auto-shutdown, data processing and report creation. Data integrity is assured with the addition of LabSolutions DB and LabSolutions CS.

Special features and benefits of the new HIC-ESP ion chromatograph are:

  • Highly effective ion-exchange performance
    The ICDS-40A is a highly efficient, electrodialytic membrane suppressor for ion chromatography. It offers stable reduction of electrical conductivity of the eluent at the time of detection, enabling high sensitivity analysis of inorganic anions.
  • Minimized peak dispersion
    The ICDS-40A anion suppressor has a smaller inner volume compared to conventional systems, resulting in less peak dispersion. It offers improved peak shape and good separation of early eluting compounds from the water dip and enables accurate measurement of e.g. fluoride that elutes early in a chromatogram.
  • Small footprint
    The HIC-ESP ion chromatography system combines with the Nexera slim oven CTO-40S for a compact design. With a width of only 420 mm, it needs just half the bench space required by other comparable systems.

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Ion ChromatographyIon chromatography, also known as ion exchange chromatography, is a high-performance liquid chromatographic technique used for the separation and identification of ions or polar molecules in a sample, including proteins, nucleotides and amino acids. Equipment includes ion exchange columns, ion exclusion columns, ion chromatography systems, pumps, and detectors. Find the best ion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.Food TestingFood testing refers to a variety experiments including PCR, mass spectrometry, processing, QuEChERS, analyzing and Kjeldahl.Environmental AnalysisEnvironmental analysis describes a variety of tests that determine the effect of chemicals, processes and particulates such as persistent organic pollutants (POPs) have on the environment.Capillary Ion ChromatographyLab EssentialsLab essentials include laboratory consumables that are vital to the operation of all laboratories.