SelectScience
Join Free
Accelerating Science
NewsLife Sciences

Protein Biology: SelectScience Special Feature

SelectScience

From optimized sample prep, imaging, and analysis to mapping the entire human proteome, discover the latest technologies, top tips, and best practices for protein biology research

4 Nov 2019
Charlie Carter
Life Sciences Editor

Editorial article

Protein Biology SelectScience Special Feature

Improved cell culture harvesting workflows

Hear from Dennis Karthaus, an IBA scientist, about how the Sartoclear Dynamics® Lab from Sartorius is designed to improve workflows by combining the clarification and sterile filtration process into one, as well as preventing contamination, to save time and ensure that the final product is pure.

Watch Video

How to determine protein stoichiometry

In this application note, BMG LABTECH has successfully adapted the Job plot to a microplate reader-based system, such as the CLARIOstar® Plus, to characterize and assess protein-protein interaction stoichiometry. This method enables the use of small sample volume and improved throughput, as up to four protein pairs can be studied in one 384-well plate.

Download Method

Mapping the whole human proteome

In this seminar, Associate Professor Jochen Schwenk discusses how bead-based affinity proteomics, using xMAP® technology from Luminex, is enabling researchers at the KTH Royal Institute of Technology, Stockholm, to map the entire human proteome.

Watch Video

Protein extraction best practices

For thermo-sensitive molecules such as proteins, sample preparation is a critical step before proceeding to molecular downstream analysis. Download this guide to learn how to achieve improved protein extraction yields for a variety of sample types using the Precellys® Evolution from Bertin Instruments.

Download Method

Monitoring biopharmaceutical impurities

Endogenous host cell proteins (HCPs) can contaminate biopharmaceutical products despite multiple purification steps in a process. Discover how micro Pillar Array Columns (µPAC™) from PharmaFluidics can be used in combination with mass spectrometry for the characterization of host cell proteins and their monitoring during downstream processing.

Download Method

Reliable buffer preparation

The manufacturing of biologics is a complex and costly process that requires optimization of process parameters to achieve and maintain product quality and purity. Find out how to use osmolality as a reliable concentration measurement method for key buffers in this application note from Advanced Instruments.

Download Method

Optimized protein staining

Save time on your protein staining and imaging protocols, and more easily visualize your proteins, using the UVP ChemStudio from Analytik Jena. Download this application note for a stain-free method for imaging proteins.

Download Method

Enhanced structural characterization

Microfluidic modulation spectroscopy (MMS) promises increased sensitivity, dynamic range, accuracy, and utility for the determination of protein secondary structure. Discover this powerful new MMS platform from RedShiftBio.

Download Method

Read the latest reviews:

Don't just take our word of it, take a look at this expert review of the Precellys® Evolution from Bertin Instruments:

Precellys Evolution by Bertin Instruments - review for protein biology special feature

Related resources:

Discover the latest protein biology news, interviews, and free downloads from SelectScience:

Hear more from the protein biology experts on the Scientists' Channel:

Related products

Request Quote for All Products

Links

SelectScienceCompany website

Tags

Protein QuantificationThe detection and quantification of proteins in a sample is vital across life sciences, pharmaceutical research and clinical diagnostics, and a variety of equipment is available to scientists to simplify the workflow. Proteins of interest can be easily labeled and detected on light-based detection instruments. Immunoassay kits allow you to identify a specific protein of interest and protein detection beads or antibody microarrays allow you to identify multiple specific proteins at once. Protein interactions and enzyme activity can also be monitored with protein-protein interaction assays. Additionally, the biophysical characterization of proteins is made easy with biokinetic analyzers. Find the best protein detection and quantification products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein ExpressionProtein expression is the utilization of cell machinery for the synthesis of proteins and has become a critical tool in biotherapeutic, genomic, and proteomic research. Produce recombinant proteins with expression vectors in combination with a host cell suitable for high-level protein expression. For production of toxic proteins, consider cell-free expression vectors. Create and monitor post-translational modifications with protein modification kits. Find the best protein expression products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Protein DetectionProtein detection techniques are essential for understanding protein expression, localization, and function. Methods such as western blotting, ELISA, and mass spectrometry are commonly used in research and diagnostics. Browse our peer-reviewed product directory to find the best tools for protein detection, compare products, check reviews, and get pricing directly from manufacturers.Protein StructureProtein structure refers to the three-dimensional arrangement of amino acids in proteins, determining their function. Understanding protein structure is key in drug discovery, enzymology, and molecular biology. Explore protein structure analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Protein PurificationProtein BiologyProtein Quantification

Related articles