New Software for Malvern’s NanoSight NTA Systems Improves User Experience and Enhances Performance

17 Jul 2014
Sarah Thomas
Associate Editor

Product news

Malvern Instruments has launched NTA 3.0, a new version of the software that drives its NanoSight Nanoparticle Tracking Analysis (NTA) systems. With an improved, easy-to-use interface, the new NTA 3.0 software makes accessing programs and protocols quick and convenient. It also incorporates an upgraded high-resolution particle size distribution algorithm, and supports advanced image analysis, particle detection and tracking, as well as providing improved vibration correction. The new software is designed for use across the complete NanoSight NTA range and will be integral to all new systems shipped, while existing users can download their free upgrade via the appropriate product page on the Malvern website:

• NanoSight NS300 www.malvern.com/ns300sw
• NanoSight LM10 www.malvern.com/lm10sw
• NanoSight NS500 www.malvern.com/ns500sw

Malvern NanoSight systems use Nanoparticle Tracking Analysis (NTA) to characterize nanoparticles in solution in the size range 10 nm to 2000 nm (depending on the sample). Each particle is analyzed individually by direct observation and measurement of diffusion events. This particle-by-particle methodology produces high resolution results for particle size distribution and concentration, while visual validation provides additional data confidence. Both particle size and concentration are measured, while a fluorescence mode provides differentiation of labeled or naturally fluorescing particles.

NTA 3.0 features automatic, integrated hardware detection and communication for all the systems in the NanoSight range. Compared with previous versions it generates fewer files per experiment and results are displayed on clear, concise spreadsheets. Particle size distributions are shown as histograms for easy interpretation.

NanoSight NTA systems are part of Malvern’s expanding portfolio for characterization at the nanoscale. By updating software for greater ease of use and more efficient testing, NanoSight NTA users can be sure of getting the best possible performance from their system.

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Particle CharacterizationParticle characterization instruments are used to determine particle size distribution, shape, surface area, zeta potential, density and porosity of particles and materials. Multiple tecchniques are available for determining particle size, shape and count including dynamic light scattering (DLS), laser diffraction, electrozone (Coulter technique), imaging particle analysis and single particle optical sensing. Determine the density of your material with a gas pycnometer or examine its surface area and porosity with gas adsorption analyzers and mercury porosimeters. Find the best particle characterization instruments in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Drug DeliveryDrug Delivery refers to dosage form, route of administration, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect. Drug delivery is often approached via the biopharmaceutical or small molecule drug's formulation, but it may also involve medical devices or drug-device combination products. Considerations include instrumentation, software and services. NanotechnologyNanotechnology, or nanotech, is an engineering technique using molecular scale functional systems. Applications of nanotechnology include medicine and medical devices, electronics, air and water purification, food science and energy production.NanoparticlesNanoparticles are between 1-100nm in size. Nanoparticles can be used for a wide variety of applications including biomedical, catalysis and electronics.