New, Inert Zebron GC Column from Phenomenex Improves Responses of Active Compounds

15 Oct 2015
Lois Manton-O'Byrne, PhD
Executive Editor

Product news

Phenomenex Inc., a global leader in the research and manufacture of advanced technologies for the separation sciences, introduces Zebron™ ZB-5MSPLUS™ – a highly inert 5% phenyl-arylene phase GC column for challenging separations in industries such as food testing, pharmaceutical and clinical research, forensic toxicology and industrial chemicals. Designed with rigorous fused-silica deactivation and quality control processes, Zebron ZB-5MSPLUS virtually eliminates active sites on the column’s surface that can negatively affect peak shapes for challenging compounds.

Most GC chromatographers are accustomed to using a 5% phenyl-arylene phase, and many work with active compounds. These researchers can switch to the new inert column for higher responses and lower detection limits, without redeveloping their methods. ZB-5MSPLUS produces better peak shapes without retention time shifts, and ultimately increases a lab’s productivity.

“GC chromatographers will often use a thicker-film column to compensate for active compounds’ proclivity to stick to the column surface,” explained Kristen Parnell, brand manager for Phenomenex. “The drawbacks of that approach can include increased run time and bleed. Our new deactivated column reduces the need to compensate for this activity.”

The new Zebron ZB-5MSPLUS is also the first of several Phenomenex GC columns that will feature completely redesigned packaging, which uses both recycled and recyclable materials and is easier to open and store.

Zebron™ ZB-5ms GC Columns

Phenomenex Inc

Low Bleed Performance for GC/MSMost popular starting column for method developersArylene Matrix Technology (AMT) provides a highly stable arylene phase for enhanced resolution of PAHs and multi-ring aromatic compoundsLow bleed (MS certified) especially suited to high sensitivity work using GC/MSRecommended UseAcids, Alkaloids, Amines, Dioxins, Drugs, EPA Methods (525, 610, 625, 8100), Essential Oils/Flavors, FAMEs, Halo-hydrocarbons, PCBs/Aroclors, Pesticides/Herbicides, Phenols, Residual Solvents, Semi-volatiles, Solvent Impurities

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Gas ChromatographyGas chromatography (GC) is an analytical technique used to separate and quantitate mixtures of small and volatile compounds. Gas chromatographs or GC systems include components such as GC columns, detectors, pumps and autosamplers. Choose from packed or capillary GC columns, flame ionization (FID), photoionization (PID) electron capture detectors and selective or non-selective detectors. Find the best gas chromatographs in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Active PharmaceuticalsThe Active Pharmaceutical Ingredient (API) of a drug is the component that causes the direct effect of the product. The remaining inactive components are known as excipients.Food TestingFood testing refers to a variety experiments including PCR, mass spectrometry, processing, QuEChERS, analyzing and Kjeldahl.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.Forensic ToxicologyForensic toxicology is used to determine cause of death, drug use and contaminations. Toxicological evaluations are commonly used in analytical chemistry, clinical, life sciences and forensics.