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Improved Version of Bruker’s TargetScreener HR 3.1 for Applied Toxicology and Forensics Unveiled

Bruker Daltonics

Bruker’s TargetScreener HR 3.1 is proposed to enhance productivity and minimize false positives and negatives

11 Jun 2018
Holly McHugh
Administrator / Office Personnel

Product news

Bruker has announced an enhanced version of TargetScreener HR 3.1, encompassing an additional 600 compounds in the field of veterinary drugs, new psychoactive substances and pesticides, resulting in a database exceeding 2,800 compounds.

All versions of TargetScreener contain TASQ™ (Target Analysis for Screening and Quantitation) software to provide a unified platform for automated screening and quantitative applications in forensic, food and environmental safety markets. TASQ uses a unique method for providing positive identifications from the highly curated database, which results in minimal false positives and false negatives, while simultaneously performing seamless quantitation.

Prof. Dr. Volker Auwärter and Dr. Laura Huppertz of the Department of Forensic Toxicology at the Institute of Forensic Medicine, University of Freiburg, Germany, commented: “TargetScreener has proved invaluable in enhancing our productivity due to the automation and the intuitive nature of TASQ. The approach minimizes false positives by combining the high mass accuracy of the impact QTOF with advanced identification and confirmation criteria. The instrument's sensitivity ensures we capture minor components even when co-eluting with highly concentrated components within the human samples we analyze, including hair samples. Furthermore, the dynamic range allows us to receive a realistic estimate of the concentrations at the same time. Regarding the cases we have to solve, and the sometimes limited sample amounts, the possibility of retrospective data evaluation is of great value to us, especially in cases involving new psychoactive substances."

Howard Taylor, PhD, Laboratory Directory at Addictions Labs of America in Brentwood, TN, stated: “Our laboratory purchased 14 Bruker compact QTOFs because of their reliability and ease of use. The TASQ software is very intuitive and extremely user friendly. Quantitation is presented with great flexibility and the user can quickly identify outliers. The TASQ software makes it easy to add new analytes for retrospective searches of new drugs.”

Find more news like this in our ASMS special feature >>

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DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Toxicology / Drugs of Abuse TestingToxicology and Drugs of Abuse Testing is the investigation into toxic and illegal substances found at the scene of a crime or from a suspect and / or victim associated with a scene of a crime. Analyzers, immunoassays and drugs of abuse test kits and presumptive test kits are an essential aspect of toxicology investigation.Food SafetyFood safety describes the prevention of food-borne illnesses. Contamination with a variety of pathogens can be prevented with adequate temperature control, hygiene and labeling. Food samples can be tested using GC/MS, HPLC, SPE, and qPCR to ensure their adherence to regulations.Food TestingFood testing refers to a variety experiments including PCR, mass spectrometry, processing, QuEChERS, analyzing and Kjeldahl.Environmental ForensicsEnvironmental AnalysisEnvironmental analysis describes a variety of tests that determine the effect of chemicals, processes and particulates such as persistent organic pollutants (POPs) have on the environment.ASMSThe American Society for Mass Spectrometry (ASMS) is an organization dedicated to advancing the science and application of mass spectrometry. ASMS supports professionals through events, publications, and research initiatives, promoting innovation in areas like proteomics, metabolomics, and environmental analysis. Forensic InvestigationForensic investigation is a diverse collection of scientific techniques and methods for the identification and characterization of chemicals relating to crime scene investigations.Forensic ToxicologyForensic toxicology is used to determine cause of death, drug use and contaminations. Toxicological evaluations are commonly used in analytical chemistry, clinical, life sciences and forensics.

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