NewsSeparations
High resolution HPLC Separations with the TSK-GEL RPC/HILIC Portfolio
1 Apr 2007
Kerry Parker
CEO
Product news
Reversed Phase Chromatography is the method of choice, when it comes to separating small molecular weight compounds.
Tosoh Bioscience offers a comprehensive portfolio of TSK-GEL RPC columns also in 2 mm ID/1 mm ID columns and 2 µm particle materials with different chemistries to fit your daily needs. Complementary to this, Tosoh Bioscience offers its HILIC phase TSK-GEL Amide-80.
Highlights of the RP and HILIC portfolio:
- Silica-based TSK-GEL RPC columns for modulation of retention. Recently developed are the 5 µm TSKgel ODS 100V and 100Z columns, with guard column system, managing the most complex sample mixtures, for use with your LC-MS system.
- Silica-based TSK-GEL Super Series RPC (Super-ODS, Super-Octyl, Super-Phenyl) columns enable rapid analysis with high resolution at low backpressure. A high value column for method development, particularly for re-validation of old methods, for FDA-registration.
- Polymer-based TSK-GEL RPC columns allow operation at basic pH where silica based columns have limited chemical stability.
- TSKgel Amide-80 HILIC columns for separation of polar/hydrophilic compounds, combining the advantages of NPC with those of RP, without having to forgo the common RP eluents.
To find out more about our RPC and HILIC TSK-GEL columns order our TSK-GEL RPC column brochure contact us or visit the article webpage.
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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
