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Gain Comprehensive T Cell Biology Insights Using Advanced Flow Cytometry

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Join this webinar for expert advice on how to gain detailed T cell characterization data through assay volume miniaturization and increased assay productivity

8 Jul 2019
Charlie Carter
Life Sciences Editor

Expert insights

The ex vivo expansion of T cells is a critical process in bio-manufacturing of adoptive cell therapies. Recent clinical studies show a correlation between persistence of subsets of functional memory T cells, including T memory stem cells (TSCM), central memory T cells (TCM) and other less differentiated T cell subsets, and long-term anti-tumor responses in patient outcomes. Technologies that can robustly and reliably provide high-content immunophenotypic and functional data are therefore critical for the rapid and robust development of new therapies.

In this upcoming SelectScience webinar, Dr. John O'Rourke will explore how a rapid multiparametric assay was developed and evaluated using the Intellicyt iQue3, an advanced flow cytometry platform, to address the need to profile T cell memory subsets and functional cytokine release.

REGISTER NOW

Watch this webinar to learn how to:

  • Miniaturize assay volumes by identifying T cells, quantitating memory subsets, assessing cell health, proliferation and cytokine secretion in a single well
  • Significantly reduce data analysis time from hours to just minutes using advanced integrated data analysis visualization tools
  • Increase assay productivity and simplify workflows using faster, smarter flow cytometry

The live webinar takes place on Thursday, July 25, 2019, at:

  • 16:00 BST
  • 11:00 EDT
  • 08:00 PDT
  • 17:00 CEST

Scheduling conflict? No matter, register to receive an on-demand link to watch later>>

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Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.ImmunoassayImmunoassays are laboratory tests that utilize antibody-antigen interactions to detect specific substances. They are widely used in diagnostics for detecting diseases, drug testing, and environmental monitoring. These assays offer rapid, sensitive, and precise detection of biomarkers, making them invaluable in clinical and research labs. Browse our peer-reviewed product directory to compare immunoassay systems, read user reviews, and get pricing directly from manufacturers.Data AnalysisThe analysis of data is the process of transforming, modeling and evaluating data to discover useful information from experimental results. Assay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.ImmunophenotypingT Cells

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