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Faced with Global Acetonitrile Shortage, Analytical Labs Turn to ACQUITY UPLC to Reduce Acetonitrile Use by at least 70 Percent

Waters
19 Dec 2008
Samantha Rosoman
Campaign Coordinator

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With the analytical industry experiencing its most severe acetonitrile shortage in history, pharmaceutical, food, environmental and chemical industries are all searching for solutions to maintain their mission critical laboratory productivity.

Waters Corporation, working with its key customers, today estimated that replacing traditional high performance LC (HPLC) with Waters® ACQUITY® UltraPerformance LC® (UPLC®) reduces acetonitrile consumption by at least 70 percent without compromising productivity and performance.

“The time for ACQUITY UPLC adoption has never been clearer,” said Rohit Khanna, Vice President of Global Marketing for the Waters Division. “Laboratory-dependent businesses and government agencies around the world are facing difficult decisions because there is simply not enough acetonitrile available to efficiently run their labs using traditional liquid chromatography technology. As these organizations evaluate their options, the innovations behind UPLC technology provide the best solution to today’s crisis and safeguarding against future risk.”

The ACQUITY UPLC System allows scientists to perform required analysis, such as quality assurance and quality control tests, using less resource than HPLC. Because the system operates with a wider velocity range, higher flow rates, and greater backpressures, UPLC uses significantly less solvent, including acetonitrile. The result is the ability to maintain or improve lab productivity and performance, with reduced costs and reduced external pressures associated with the current acetonitrile shortages.

For more information on ACQUITY UPLC, method validation, and related case studies, please visit the company website.

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ACQUITY UPLC System

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Waters ACQUITY UPLC - Dramatic Improvements in Speed, Sensitivity and Resolution Whether you work in methods development or quality assurance, in drug discovery and development or testing for safety in food supplies, you seek a productivity edge. With the ACQUITY UPLC® System, now you can get more information in a single, short run than you've ever seen with HPLC. Waters ACQUITY UPLC System UltraPerformance LC® (UPLC®) technology starts with unique 1.7 μm small-particle chemistries. Chromatographers no longer need to choose between speed and resolution–with UPLC you get both. Instrument Designed for Chemistry; Chemistry Designed for the Instrument The ACQUITY UPLC System has been holistically designed to match the performance needs of our innovative column chemistries with robust hardware, easy-to-use software and specialized support services. Small, pressure-tolerant particles High-pressure fluidic modules Minimized system volume Negligible carryover Reduced cycle times Fast response detectors Integrated system software and diagnostics With UPLC you have the ability to work more efficiently with higher speed, sensitivity and resolution at a much wider range of linear velocities, flow rates and backpressures to obtain superior results. The Waters ACQUITY UPLC System's high-pressure fluidics optimizes flow rates to make the most of small particle technology. The ACQUITY UPLC System's sample-handling design is designed to ensure exceptionally low carryover and reduced cycle time. And when interfaced with the Sample Organizer, it increases unattended sample capacity by ten times. High-speed detectors, both optical and mass, contribute to increased sensitivity and help manage the heightened speed and resolution requirements of UPLC. ACQUITY UPLC Systems are easily controlled, diagnosed, and monitored via a graphical system console interface. The console offers: Quick and easy access to critical instrument parameters Simple system start-up, elegant system status monitoring and predictive performance indicators to ensure maximum productivity Data management capabilities that are supported by both MassLynx™ and Empower™ software The ACQUITY UPLC System is also supported by Intelligent Device Management technology with our Connections® INSIGHT™ service, providing instrument diagnostics.

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