Eppendorf and Florida State University Collaboration Demonstrates Large-Scale Stem Cell Expansion

18 Mar 2015
Sarah Thomas
Associate Editor

Product news

A collaboration between Eppendorf and Florida State University has successfully shown the feasibility of large-scale expansion of human mesenchymal stem cells (MSC) using the company’s proprietary Fibra-Cel® packed-bed technology.

Dr. Ma Sha, Director of Technical Applications at Eppendorf, provided equipment and funding for reagents to Dr. Teng Ma to support the Florida State team’s work in the field of stem cell expansion. The team successfully conducted MSC expansion inside a packed-bed 3D matrix using a CelliGen® 310 bioreactor at ~2 L scale. The results demonstrate the feasibility of large-scale stem cell expansion using the company’s patented Fibra-Cel packed-bed technology which provides uniform mass transfer of nutrients and oxygen to the adhered cells. The finding will be submitted for publication at a peer reviewed scientific journal.

Dr. Yaw D. Yeboah, Dean and Professor, College of Engineering, thanked Eppendorf and noted that the company’s commitment to the University allows it to continue to deliver world-class education and transformative experiences that prepare students for the challenges of today’s complex, knowledge-driven marketplace.

Fibra-Cel® Disks

Eppendorf

Fibra-Cel disks are a proven support system used to increase yields of suspension and anchorage-dependent cultures. Fibra-Cel is also available for use in disposable bags, shake flasks and other bioreactor systems. 

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Eppendorf BioFlo® 320

Eppendorf

 The BioFlo 320 seamlessly blends beauty and utility in one all-inclusive package. A new industrial design, flexibility between interchangeable autoclavable and single-use vessels, intelligent sensors, Ethernet connectivity, and a new software package are only a few of the features that set it apart from the competition

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.Mesenchymal Stem Cells