BMG LABTECH Presents its Revolutionary Microplate Reader Technology at EMBL Symposia

27 May 2015
Lauren Edwards
Editorial

Product news

BMG LABTECH - the microplate reader company - showcases its multimode microplate reader CLARIOstar with unique LVF MonochromatorTM technology and new Atmospheric Control Unit (ACU). Visit booth #1 at EMBL Heidelberg from 14th to 17th of June.

The CLARIOstar® multimode microplate reader offers filter-like performance with advanced LVF MonochromatorsTM providing increased sensitivity over conventional monochromators. The LVF MonochromatorsTM, along with filters and an UV/ Vis spectrometer can be used for a variety of applications in up to eight different detection modes: Fluorescence Intensity and FRET, Time-Resolved Fluorescence (TRF) and TR-FRET, Fluorescence Polarization/Anisotropy, AlphaScreen®/AlphaLISA®, Luminescence (flash and glow) and BRET, and spectrometer-based UV/Vis absorbance.

Equipped with the Atmospheric Control Unit the CLARIOstar® is able to provide the physiological environment for any cell type. The microprocessor-controlled unit can regulate CO2 and O2 independently from 0.1% to 20%, making it unnecessary to use premixed gas cylinders to reproduce the specific physiological conditions needed for cell-based assays. The integration of the ACU into the reader control software allows users to effortlessly regulate the gas concentrations within the microplate reader chamber. The gas concentration data is recorded over the measurement time and displayed in the MARS Data Analysis Software. In combination with CLARIOstar®’s extended temperature control and three different shaking options (orbital, double orbital, and linear), the ACU is able to provide the physiological environment for any cell type, making cell-based assays more biologically relevant.

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Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.