Axion BioSystems introduces new high-throughput, multiplate Maestro TrayZ Platform

4 Oct 2022
Ellen Simms
Product and Reviews Editor

Product news

Axion BioSystems has announced the Maestro TrayZ, an innovative, live-cell analysis platform designed for high-throughput drug development and therapeutic discovery. The new system—featuring a slim multiplate tray design that allows for modular scalability and fits comfortably inside an incubator—joins Axion’s growing suite of next-generation Maestro products and offers a flexible, affordable option for noninvasive, label-free monitoring of live cells in real time.

“The paradigm-shifting Maestro TrayZ platform meets growing customer demand for a high-throughput, cost-effective tool that can help bring novel cell-based treatments to the market faster,” stated Kevin Gould, Axion BioSystems’ CEO. “I applaud Axion’s remarkable product development team for this achievement and expect the new system will quickly become indispensable for scientists and drug developers.”

According to Axion’s President and CTO Jim Ross, the scalable tray design is a gamechanger for users. “The Maestro TrayZ platform provides a great deal of flexibility, allowing users to add trays to increase the throughput to meet their needs and easily run multiple experiments in a controlled, GMP-compatible environment. This high-throughput capacity, combined with Axion’s signature intuitive controls, powerful software, and automated tracking keeps the increased throughput from increasing the workload, making the system a great fit for any discovery and manufacturing workflow.”

Today’s complex cell-based therapeutics, such as CAR T cell therapies for immuno-oncology applications, demand powerful in vitro assays that can accurately characterize cellular interactions during preclinical development and ensure product consistency throughout the manufacturing process. While conventional assays are limited to a single snapshot in time and can miss important markers of cellular activity, Axion BioSystems’ label-free, noninvasive Maestro TrayZ—which uses sensitive bioelectrodes to continuously monitor the potency of immune cell-mediated killing—enables scientists to efficiently test new therapeutic candidates and maintain the quality of cell-based products in real time. Designed with a regulatory environment in mind, Maestro TrayZ boasts GMP-compliance software, barcode plate tracking, environmental monitoring, and automated event logging.

“Since the launch of the original Maestro Z in 2020, we have been gratified to see how scientists around the world are using our systems to accelerate the development of urgently needed immunotherapies, identify potential antivirals, and investigate other complex cellular behavior in vitro,” added CEO Kevin Gould. “The Maestro TrayZ takes it to the next level, and we look forward to seeing how users will continue to break new ground.”

Want the latest science news straight to your inbox? Become a SelectScience member for free today>>

Links

Tags

Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Live Cell ImagingLive cell imaging is the study of living cells using microscopes and high-content imaging systems. This technique provides in-depth insight into fast and complex biological processes, by allowing dynamic imaging of living cells instead of acquiring an individual image at a single point in time.Label-Free AnalysisTherapeuticsTherapeutics are treatments designed to alleviate or cure diseases. These include pharmaceuticals, biologics, and gene therapies, which work by targeting specific disease mechanisms. Advances in personalized medicine and biologics offer new hope for patients with conditions that were previously difficult to treat. Browse our peer-reviewed product directory to find therapeutic solutions for various diseases; compare products, check user reviews, and get pricing directly from manufacturers.Drug DevelopmentDrug development refers to the process of bringing a new drug to market.