Maestro TrayZ
Multiplate live-cell analysis system
Maestro TrayZ system
Maestro TrayZ inside an incubator
Receive your quote directly from the manufacturer.
The Maestro TrayZ™ is a sensitive, live-cell impedance platform for real-time measurement of cell health and function. Continuously monitor up to four 96-well plates simultaneously and generate accurate, reproducible kinetic data using cellular impedance. It features a slim, multiplate tray designed to easily fit in an incubator without requiring the whole incubator.
With easy-to-run assays and clear results, the Maestro TrayZ platform is ideal for cytotoxicity, cell growth, adhesion, immune cell-mediated killing, TEER/barrier function, wound healing, GPCR signaling, viral cytopathic effects, and more. Save time, cut costs, and simplify your workflow with Maestro TrayZ.
Discover ground-breaking throughput, power, precision, and control in the first commercially available multiwell optical stimulation device. Incorporate cutting-edge optical techniques into your in vitro research using Axion BioSystems’ Lumos.
For Research Use Only. Not for use in diagnostic procedures.
KEY FEATURES
- Continuous live-cell monitoring — The Maestro TrayZ platform performs noninvasive, label-free electrical measurements from the cultured cell population, circumventing the use of dyes/reporters that can perturb your cell model and confound results. Track activity in real time over hours, days, and weeks.
- Expand to meet your needs — With one tray, measure up to four plates at once, or link multiple trays together to increase your throughput to meet your needs.
- Manage multiple experiments at the device — Barcode tracking ensures there are no mix-ups. As soon as a plate is docked, recording begins without having to run back and forth to a computer.
- Review your results faster — The Impedance module with AxIS Z™ software provides a simplified approach to the setup, execution, and analysis of experiments.
Multiplex your assay: Maestro + Omni™
- Platform cross-compatibility lets you view live-cell imaging alongside real-time, functional data to enhance your analysis.
- Monitor electrode coverage and cell morphology to ensure consistent, quality results.
- Experience no-hassle tracking — the Axion Portal automatically links data via barcode.
SOFTWARE
The Maestro TrayZ system is available with the Impedance Software Module:
- Impedance – Track cell proliferation, morphology, and viability label-free and in real-time. Ideal for immuno-oncology, cytotoxicity, virology, cell migration, cell proliferation, GPCR assays, and many more.
CONSUMABLES
The Maestro TrayZ system is compatible with the 96-well impedance assay plate.
- CytoView-Z™ – The Maestro impedance plate with a transparent well bottom for cell visualization and assay multiplexing. Available in a 96-well plate format.
CROSS-COMPATIBLE PLATFORMS
The Maestro Edge system has cross-compatibility with:
- Omni – Compliment your impedance assays with whole-plate images of your cultures. View electrode coverage and culture health over time with just a few clicks in AxIS Z. Compatible with the Omni and Omni Pro 12™ systems.
Brochures
Immunotherapy development: Live-cell tools to accelerate discovery
In this brochure, Axion BioSystems provides information about live-cell tools and technologies for accelerating immuno-oncology research and development. The company's products utilize live-cell assays for a more complete picture of experiments and easier optimization of processes, identification of best candidates, and reliable preclinical data. Axion BioSystems' live-cell platforms allow for the evaluation of in vitro immune cell killing, tumor cell biology, and migration and invasion. The platforms offer whole-well brightfield or fluorescence imaging with single or multiplate options and are compatible with incubators.
Maestro TrayZ: The scalable live-cell assay system
In this brochure, Axion BioSystems introduces the Maestro TrayZ, the latest in bioelectronic engineering. With a thin multiplate design developed to accommodate multiple trays in an incubator, you can turn any standard incubator into an assay powerhouse.
Multiplate cell-based assays with Maestro TrayZ for cytotoxicity and potency
See how Maestro TrayZ delivers real-time, reproducible data without sacrificing throughput. Explore our new application note to learn how label-free cytotoxicity and potency assays can support your workflow.
Quantifying NK-mediated cytolysis of glioblastoma in vitro with Maestro Z
Immunotherapies such as CAR T cells that have shown success in treating liquid tumors have had limited efficacy against solid tumors, including glioblastoma. Natural killer (NK) cells represent a promising approach for solid tumor treatment, and understanding mechanisms of NK-mediated cytotoxicity is important for cell therapy development. In this application note, Axion Biosystems quantifies the kinetics of both antibody-dependent cellular cytotoxicity (ADCC) and CAR NK-mediated cytolysis against glioblastoma cells using the Maestro Z. Kinetics of these mechanisms are assessed across multiple target cell lines and effector:target ratios.
Antibody-dependent cellular cytotoxicity of natural killer cells
Trastuzumab promotes natural killer cell activation through antibody-dependent cellular cytotoxicity (ADCC). Understanding ADCC can help researchers develop immunotherapies with better targeting and efficacy. In this application note, Axion Biosystems examines and quantifies ADCC-specific killing using the monoclonal antibody trastuzumab and peripheral blood natural killer cells on the Maestro z. The ADCC response between donors and across multiple effector to target cell ratios is compared.
CAR T cell potency assessment with 3D cancer spheroid models
In this application note, Axion Biosystems uses the Maestro Z to develop a real-time, label-free potency assay for immune-cell mediated killing of 3D cancer spheroids.
