Ananda Devices, Molecular Devices collaborate to automate imaging and customize analysis of nervous system on-a-chip

Ananda Devices and Molecular Devices have announced at the SLAS2021 virtual conference that the two companies have entered a strategic collaboration involving the NeuroHTSTM nervous system on-a-chip platform and the ImageXpress^® Pico Automated Cell Imaging System. Combined, the technology will enable automated screening and custom analysis of neuronal growth and connections in NeuroHTSTM microplates, offering scientists reliable and reproducible research results.

“There is an enormous need to make high-performance neuroscience solutions more accessible to the broader scientific community,” said Margaret Magdesian, CEO of Ananda Devices. “The flexible and highly quantitative ImageXpress Pico system and its custom analysis algorithms provide all the necessary tools to realize the full potential of the NeuroHTSTM plates in automation of neuronal analysis. We are excited to align ourselves with an innovation powerhouse like Molecular Devices, together helping our customers accelerate their neuroscience discoveries.”

NeuroHTSTM is a leading high-throughput in vitro platform for neuronal network formation and screening, featuring precise nano-scale organization of neurons for enhanced reproducibility and physiological relevance of cellular assays. In addition to automation of neurodegeneration and growth assays, NeuroHTSTM enables analysis of neuronal network dynamics.

The ImageXpress Pico system is adept at automated imaging of non-standard plate formats while maintaining robust focus across the acquisition. In combination with NeuroHTSTM microplates, neuroscientists can now image and analyze over 3,000 neurons in less than 30 minutes with very high sample-to-sample reproducibility.

“With its high-resolution imaging and powerful analysis capabilities, the ImageXpress Pico system is ideal for generating meaningful, multiparametric readouts of NeuroHTSTM microplates to characterize neuronal network dynamics for researchers,” said Celeste Glazer, Vice President of Global Marketing and Product Management at Molecular Devices. “Through our collaboration with Ananda Devices, we look forward to supporting continued advancement in neuroscience with our innovative imaging portfolio.”

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