SNF5 rabbit antibody (pAb), sample
SNF5 (Sucrose Non Fermenting 5, also called INI1, BAF47 and SMARCB1) is a tumor suppressor protein that is a component of the SWI/SNF chromatin-remodeling complex that regulates gene expression through alterations in chromatin structure. Alterations in chromatin structure facilitated by ATP-dependant chromatin remodeling machines are thought to enhance recognition and binding of trans-acting factors that bind DNA and regulate transcription. SNF5 signals through the p16INK4a pathway to negatively regulate cell cycle progression and mediate chromosome stability. Mutations in SNF5 are a cause of malignant rhabdoid tumors in children.
Product Details
- Cat. No.
- 39776
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Reviews
Applications
- Western Blotting (WB)
Antibody Overview
About the company
Active Motif
Active Motif is the industry leader in developing and delivering innovative tools to enable epigenetics and gene regulation research. We are committed to providing the highest quality products and superior service & support to serve the life science, clinical and pharmaceutical/drug discovery communities. Whether you are an expert in the field of epigenetics or a researcher interested in integrating epigenetics research into your studies, Active Motif offers a comprehensive portfolio of epigenetics-related products and services and the support of our team of epigenetic experts to provide complete and innovative solutions to tackle your scientific inquiries.