Histone H3R17me2a (asymmetric) rabbit antibody (pAb), sample
The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histones are subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation. These modifications play a major role in regulating gene expression. Methylation of arginine 17 by the co-activator protein CARM1/PRMT4 is involved with transcriptional activation by nuclear receptors.
Product Details
- Cat. No.
- 39710
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Reviews
Applications
- Dot Blot (DB)
- Western Blotting (WB)
Antibody Overview
About the company
Active Motif
Active Motif is the industry leader in developing and delivering innovative tools to enable epigenetics and gene regulation research. We are committed to providing the highest quality products and superior service & support to serve the life science, clinical and pharmaceutical/drug discovery communities. Whether you are an expert in the field of epigenetics or a researcher interested in integrating epigenetics research into your studies, Active Motif offers a comprehensive portfolio of epigenetics-related products and services and the support of our team of epigenetic experts to provide complete and innovative solutions to tackle your scientific inquiries.