EZH2 mouse antibody (mAb) (Clone AC22)
EZH2 is a human homolog of the Drosophila Polycomb-group protein Enhancer of Zeste protein, and contains a SET domain that catalyzes the methylation of histone H3 at lysine 27. Polycomb-group proteins repress gene expression by binding to chromatin and locally altering chromatin structure. EZH2, BMI-1 and SUZ12 are present in the PRC2 and PRC3 protein complexes that function as mediators of epigenetic transcriptional silencing. Deregulation of EZH2 is linked to a variety of cancers.
Product Details
- Cat. No.
- 39875
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Reviews
Mixed results
RNA Immunoprecipitation
Mixed results in RNA Immunoprecipitation experiments
Review Date: 17 Mar 2023 | Active Motif
Applications
- Chromatin Immunoprecipitation (ChIP)
Antibody Overview
About the company
Active Motif
Active Motif is the industry leader in developing and delivering innovative tools to enable epigenetics and gene regulation research. We are committed to providing the highest quality products and superior service & support to serve the life science, clinical and pharmaceutical/drug discovery communities. Whether you are an expert in the field of epigenetics or a researcher interested in integrating epigenetics research into your studies, Active Motif offers a comprehensive portfolio of epigenetics-related products and services and the support of our team of epigenetic experts to provide complete and innovative solutions to tackle your scientific inquiries.