Bcl3 rabbit antibody (pAb), sample
Bcl3 (B-cell lymphoma 3 protein) functions as a transcriptional co-activator that activates through its association with NFkB homodimers. Bcl3 contains seven ankyrin repeats, which are most closely related to those found in IkB proteins. Bcl3 also functions as a form of IkB specific for the NFkB p50 subunit inhibiting its translocation to the nucleus. The expression of this gene can be induced by NFkB, which forms a part of the autoregulatory loop that controls the nuclear residence of NFkB p50. Bcl3 is overexpressed in a number of cancers, can transform fibroblasts and induce tumors in nude mice, thus implicating Bcl3 as a proto-oncogene.
Product Details
- Cat. No.
- 39762
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Reviews
Applications
- Western Blotting (WB)
Antibody Overview
About the company
Active Motif
Active Motif is the industry leader in developing and delivering innovative tools to enable epigenetics and gene regulation research. We are committed to providing the highest quality products and superior service & support to serve the life science, clinical and pharmaceutical/drug discovery communities. Whether you are an expert in the field of epigenetics or a researcher interested in integrating epigenetics research into your studies, Active Motif offers a comprehensive portfolio of epigenetics-related products and services and the support of our team of epigenetic experts to provide complete and innovative solutions to tackle your scientific inquiries.