ASPM / MCPH5 rabbit antibody (pAb)
ASPM (abnormal spindle-like microcephaly associated, microcephaly primary type 5, MCPH5) is a protein that participates in spindle organization, spindle positioning and cytokinesis in all dividing cells. ASPM / MCPH5 localizes to centrosomes, spindle poles, and the spindle midbody. It regulates the orientation of the mitotic spindle, which controls whether cells divide symmetrically or asymmetrically. ASPM / MCPH5 is highly expressed in many tumor cell lines and mutations in the gene encoding ASPM / MCPH5 lead to primary microcephaly in humans.
Product Details
- Cat. No.
- 61205
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Reviews
Applications
- Immunofluorescence (IF)
Antibody Overview
About the company
Active Motif
Active Motif is the industry leader in developing and delivering innovative tools to enable epigenetics and gene regulation research. We are committed to providing the highest quality products and superior service & support to serve the life science, clinical and pharmaceutical/drug discovery communities. Whether you are an expert in the field of epigenetics or a researcher interested in integrating epigenetics research into your studies, Active Motif offers a comprehensive portfolio of epigenetics-related products and services and the support of our team of epigenetic experts to provide complete and innovative solutions to tackle your scientific inquiries.