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The µPAC™ Column: Unprecedented Separation Power with a Compact Form

4 Jul 2018
The µPAC™ Column: Unprecedented Separation Power with a Compact Form

In this video, discover how the µPAC’s micromachined separation bed technology produces a miniaturized, high-performance separation tool compatible with all Nano-LC-MS equipment. The µPAC's design makes it ideal for small volumes of complex samples, such as in biomarker identification and biopharmaceutical development.

About the company

PharmaFluidics logo

PharmaFluidics

PharmaFluidics develops and commercializes a unique µPAC™ range of micro-Chip based chromatography columns for use in biomarker, diagnostics and drug research & development applications in the global biotech and pharma industries.

The key expertise of PharmaFluidics are the design, lithographic production, and surface treatment of silicon wafers for use as separation devices in liquid chromatography. The µPAC™ columns are made by etching and have a separation bed of highly ordered and free-standing pillars.

The unprecedented robustness, the game-changing sensitivity and separation performance of PharmaFluidics’ µPAC™ chromatography columns allows the analytical scientist to identify more compounds in complex biological samples, such as biopsies, proteome digests or bio-pharmaceutical actives.

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200 cm µPAC™ column

PharmaFluidics

As an alternative to conventional columns, PharmaFluidics offers micromachined nano-LC columns or micro Pillar Array Columns (µPAC™). These µPAC™ columns display exceptional separation properties with unprecedented peak capacity and narrow peak shapes at low operating back-pressure. µPAC™ column, 200 cm length, with pillar array backbone at interpillar distance of 2.5µm, C18.

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50 cm µPAC™ column

PharmaFluidics

With an internal volume of 3µL, this 50 cm long RP-C18 µPAC™ column is perfectly suited to perform high throughput analyses with shorter gradi­ent solvent times (30, 60 and 90-minute gradients) and it can be used over a wide range of flow rates, between 100 and 2000 nL/min. µPAC™ column, 50 cm length, with pillar array backbone at interpillar distance of 2.5µm, C18.

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