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Monoclonal antibody purification with the MAGicAccio Process system

23 Sept 2024
Monoclonal antibody purification with the MAGicAccio Process system

Monoclonal antibodies (mAbs) are crucial for treating various diseases, but traditional purification methods struggle with cost and yield. Explore MAGic Bioprocessing's MAGic™Accio Process system, a new magnetic bead-based separation platform that automates the entire process, enhancing efficiency and reducing impurities.

About the company

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MAGic BioProcessing

MAGic BioProcessing AB is a biotech tools company from Uppsala, Sweden that develops and sells proprietary magnetic-based products and methods for bioprocessing of biologics such as recombinant proteins, monoclonal antibodies, viral vectors and cells. Our mission is to help to make the best biologics by introducing our magnetic separation based methodology to improve throughput and yield while decreasing production cost and streamline the downstream process of high-valuable biologics.

MAGic™Accio System Process

MAGic BioProcessing

MAGic™Accio PROCESS are our large fully automated magnetic separator systems, made for efficient capture of 1-40 liters of MAGic™Beads magnetic beads from large volumes of complex feedstocks. During the production phase of biopharmaceuticals, large-scale recovery of the product from an unclarified cell-culture is performed in a one-step clarification and purification by using the proprietary designed MAGic™Accio PROCESS units together with our MAGic™Beads. The magnetic separators are capable to capture up to 40 liters of MAGic™Beads at high flow rates making them suitable to process up to kilograms of proteins or antibodies per purification cycle and fully integrated in existing manufacturing workflows.

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Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Monoclonal AntibodiesMonoclonal antibodies (mAbs) are lab-made molecules that can bind to specific antigens on cells, making them highly effective in treating cancers, autoimmune diseases, and infections. These targeted therapies are transforming the treatment landscape for many conditions. Browse our peer-reviewed product directory to find monoclonal antibodies for research and clinical applications; compare products, check reviews, and get pricing directly from manufacturers.
Monoclonal antibody purification with MAGic Accio Process system