Introducing Novel Gold-Sol Technology
9 Dec 2008
BioAssay Works introduce unique gold and gold/silver particles for use in rapid assay, lateral flow assays, and nanoparticles for light-scattering, microarray and other nanoparticle based assays.
BioAssay Works introduce unique gold and gold/silver particles for use in rapid assay, lateral flow assays, and nanoparticles for light-scattering, microarray and other nanoparticle based assays.
BioAssay Work LLC technical innovations saves you development time and money. Key services include contract assay development, contract manufacturing, antibody development, lateral-flow component optimization and reagent supply.
10 OD to 50 OD concentrated nanoparticles that have been optimized for rapid assays without the traditional boiling and centrifugation steps. The BioAssay Works gold sol production process is unique, by eliminating the boiling step, and because of the concentrated gold, you do not have to dilute the sols prior to conjugation, nor do they have to be centrifuged to remove free antibody. The elimination of these two steps alone immediately contributes to the gold sol consistency, reduction of assay development problems and cost savings for manufacturing. The proprietary process reduces the problem of polymers and aggregates, and this optimizes performance in your rapid assays.
Gold-in-a-Box is an easy-to-use kit for preparing highly reactive gold conjugates. The Gold-in-a-Box kit enables users to quickly determine (in less than one hour) the optimal colloidal gold binding conditions for attaching soluble proteins, and the Fc portion of purified monoclonal and polyclonal antibodies, without the need to boil gold or centrifuge conjugate. The resulting gold particles are highly active and greatly increase the sensitivity of lateral-flow tests. It contains BioAssay Works Naked Gold and all the buffers, blocking solution and protocol for optimal coating. In addition, the drying buffer is supplied with treated polyester conjugate pad ribbon. Also, available separately, is a treated ribbon to produce an optimized gold conjugate pad. Customized components are available upon request. The Gold-in-a-Box kit helps you determine the ideal iso-electric point of the coating antibody for optimal binding to the proprietary BioAssay Works gold sols.
The Iso-Gold kit is a rapid-format isotyping kit that reduces the labor of the traditional ELISA kit from a day-and-a-half procedure to a five-minute assay. It determines the isotype of your monoclonal antibody, assess the purity of your purified monoclonal antibody*, verify the purity of your purchased monclonal antibody* and reduces runtime. *multiple lines appear and indicate subclass contamination
BioAssay Works' Tell-Tale gold impregnated ribbon has conjugated Protein A and Protein G concentrated gold particles dried in a proprietary process that ensures rapid release and increased sensitivity. This gold ribbon can be offered with gold dried at custom concentrations to meet specific assay requirements, for any monoclonal, polyclonal antibody or soluble protein.
Patented lateral-flow platform contributes to an increased sensitivity, with a rapid assay platform that avoids current patent constraints. Not only is it a new patented platform, but the increased performance of this assay platform can offer you ELISA-like sensitivity in a lateral-flow format.
BioAssay Works offers extensive experience to conjugate specified ligands (conjugating soluble proteins, haptens, hydrophobic proteins, viral and bacterial proteins) to BioAssay Works novel gold sols to speed assay research.
The Au/Ag particles have increased advantages in light or laser applications, when taking light scattering measurements. The BioAssay Works silver/gold nanoparticles and conjugates production process is unique, by eliminating the boiling step, and because of the concentrated gold, you do not have to dilute the sols prior to conjugation, nor do they have to be centrifuged to remove free antibody. The elimination of these two steps alone immediately contributes to the gold sol consistency, reduction of assay development problems and cost savings for manufacturing. The proprietary process reduces the problem of polymers and aggregates and this optimizes performance in your rapid assays.
