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Challenges and solutions for early recognition and treatment of sepsis

Global Sepsis Alliance
16 Jan 2025
Challenges and solutions for early recognition and treatment of sepsis

This presentation from the 2024 World Sepsis Congress Spotlight: Unmet Need in Sepsis Diagnosis and Therapy explores challenges and solutions for the early recognition and treatment of sepsis. Topics discussed include how electronics can support the triage of severely unwell patients, how a preclinical checklist can aid early sepsis detection, and risk factors and treatment for delayed sepsis presentation.

00:00:00 Introduction
00:03:11 Patrick de Marie Katoto, Catholic University of Bukavu, Democratic Republic of Congo – ARCS: Understanding Risk Factors for Delayed Presentation and Care of Sepsis Patients in DRC, Nigeria, and Sierra Leone
00:17:27 Wiltrud Abels, Charité – Universitätsmedizin Berlin, Germany – Sepsis Check – A Preclinical Checklist for Early Detection and Education
00:32:51 Glenn Hernandez Poblete, Pontifical Catholic University of Chile, Chile – Early Resuscitation of Septic Shock in the ED – Which Perfusion Parameters for Target Resuscitation?
00:45:37 Flavia Machado, Latin American Sepsis Institute, Brazil – Sepsis in Brazilian Emergency Departments: A Prospective Multicenter Observational Study
01:00:28 Mark Ansermino, BC Childrens Hospital, Canada – Smart Triage: Electronic Support for Early Recognition and Triage of Severely Ill Patients in Ugandan Emergency Departments
01:12:26 Michael Wong, Physician Patient Alliance for Health and Safety, USA – Closing Remarks

About the company

Global Sepsis Alliance

The Global Sepsis Alliance (GSA) is a non-profit charity organization with the mission to provide global leadership to reduce the worldwide burden of sepsis. The GSA is the initiator of World Sepsis Day on September 13 and World Sepsis Congress, a series of free online congresses bringing knowledge about sepsis to all parts of the world, among other initiatives.

The GSA works closely with its over 120 member organizations from all over the world – patient advocacy groups, professional societies, healthcare authorities, and governments – to implement changes on how sepsis is prioritized, diagnosed, and treated all around the world, as laid out in the WHO Resolution on Sepsis.

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Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Clinical MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Point-of-CarePoint-of-Care Testing (POCT) or Near Patient Testing (NPT) products are available for urine, blood and other clinical chemistry analyses. POCT includes: blood glucose testing, blood gas and electrolytes analysis, rapid coagulation testing (PT / INR), rapid cardiac markers diagnostics, drugs of abuse screening, urine strips testing, pregnancy testing, fecal occult blood analysis, food pathogens screening, hemoglobin diagnostics, infectious disease testing and cholesterol screening.HematologyIn Haematology / Hematology, complete blood cell counts (or full blood counts) are obtained using automated blood count analyzers to enumerate blood cell types.  Hematology also encompasses haemostasis and coagulation, thrombophilia and hemophilia, plasma viscosity and ESR analysis, hemoglobinopathies, cell morphology and haematinic measurement.SepsisSepsis is a life-threatening response to infection causing organ dysfunction. Research focuses on early detection, biomarkers, and therapies to reduce mortality. Explore tools for sepsis diagnostics and analysis in our peer-reviewed product directory, including detection kits and biomarkers.World Sepsis Congress SpotlightSelectScience is honored to host session from the 2024 World Sepsis Congress Spotlight, in collaboration and support of the Global Sepsis Alliance. Watch these open access presentations, talks and discussions to understand the current situation around laboratory sepsis diagnostics, sepsis therapy and management, and the global sepsis agenda.

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