SelectScience InterviewsClinical Diagnostics

Bruker set to bring chromatography-free diagnostics to the masses

23 Jun 2025
Bruker set to bring chromatography-free diagnostics to the masses

Jeff Zonderman, Vice President of Bruker Applied Mass Spectrometry, unveils major strides in clinical diagnostics with the acquisition of RECIPE, a leading provider of mass spectrometry diagnostic kits for small molecule analysis. Combined with Bruker’s DART (Direct Analysis in Real Time) technology, this move enables the development of fully integrated, chromatography-free mass spectrometry workflows tailored to clinical laboratories.

These innovations—centered around the EVOQ DART TQ+ system—promise higher throughput, reduced solvent use, and simplified workflows, making mass spectrometry more accessible to a wider range of labs. Clinical areas of focus include therapeutic drug monitoring, toxicology, and drugs of abuse, with Bruker working toward a future where mass spectrometry functions more like a traditional clinical analyzer.

With a proven track record in simplifying complex instrumentation—like the industry-leading MALDI Biotyper—Bruker is once again breaking down barriers to clinical adoption. By removing chromatography from the equation, the company is delivering greener, faster, and easier diagnostics for the real-world needs of today’s laboratories.

Watch to learn how Bruker is reshaping the future of clinical mass spectrometry.

About the company

Bruker Daltonics logo

Bruker Daltonics

Bruker Daltonics is dedicated to revolutionizing the field of molecular exploration. Our innovative solutions equip scientists with cutting-edge tools to delve deeper into the molecular realm and drive advancements in life sciences and biotechnology. Join us in our mission to push the boundaries of scientific discovery. The timsTOF series introduces the next generation of ion mobility technology. Trapped Ion Mobility Spectrometry (TIMS) adds an additional dimension of separation and delivers unprecedented specificity and sensitivity. The timsTOF Pro 2 with PASEF® technology delivers fast scanning speeds, making MS-based proteomics a reality, allowing the identification and quantification of thousands of proteins. The timsTOF SCP optimizes ion transfer with a new source geometry, expanding the horizons of single-cell proteomics and immunopeptidomics. The timsTOF fleX combines the power of MALDI technology with the added dimension of spatial resolution, enabling the groundbreaking field of SpatialOMx® on one platform. The MALDI-2 and microGRID options add unparalleled sensitivity and robustness for imaging experiments with cell-level resolution. With TIMS technology, the timsTOF series has unlocked a fourth dimension of analysis, enabling 4D-Proteomics™, 4D-Multiomics, and SpatialOMx®. From proteomics to metabolomics, lipidomics, and spatial omics, Bruker’s mass spectrometry solutions deliver breakthrough discoveries and deeper insights. With technology such as TIMS, smartbeam, scanning lasers for MALDI-MS Imaging, and eXtreme Resolution FTMS (XR) capable of revealing Isotopic Fine Structure (IFS) signatures, Bruker empowers scientists to drive innovation with precision.

4.6/5.0
|57 Reviews

EVOQ DART-TQ+

Bruker Daltonics

The EVOQ® DART-TQ⁺ is the world's first triple quadrupole MS system specifically designed for DART ion source plug-and-play operation. This innovative system allows for the screening and quantitation of samples with exceptional speed, ultra-high sensitivity, and a reduced environmental impact. If conventional LC-MS workflows are required, you can switch from the integrated DART source to the VIP-HESI source in seconds.

(1)

Other videos from Bruker Daltonics

Links

Tags

Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Clinical Mass SpectrometryMass spectrometry is emerging as a superior method of analysis over the longstanding, gold standard of immunoassay. Clinical mass spectrometry systems are increasingly accessible to medical laboratories and are capable of providing results with more speed and less expense than traditional methods. From simple mass spectrometers to IVDR class A compliant, highly sophisticated systems performing liquid chromatography tandem mass spectrometry (LC/MS/MS), find the latest product news, reviews and resources to make a purchasing decision for your laboratory. ToxicologyDrugs of AbuseA drug of abuse is a drug that has been taken for non-medical purposes. Such drugs can have mind-altering effects, with some causing dependence and addiction.Therapeutic Drug Monitoring