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Your freeze-drying laboratory guide from BUCHI

BUCHI
18 Mar 2025

Lyophilization is commonly used as a solution for sample preparation, sample formulation, or to improve storage properties. A wide variety of systems, with a range of sizes, capabilities, and configurations, is available on the market. No system will be suitable for every possibility, and it is important to define what the freeze dryer will be needed for, so that an appropriate instrument can be found.

Explore insights from BUCHI on how to balance individual factors to successfully freeze-dry, and learn how to address misunderstandings through technical notes and answers to frequently asked questions.

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Lyovapor™ L-300

BUCHI

With Infinite-Technology™ the Lyovapor™ L-300 is the first continuous sublimation system available on the market. The instrument contains two alternating condensers that operate at -105 °C and undergo automatic hygenic cleansing. In addition, Infinite-Control™ allows entire process control of all relevant parameters via mobile devices or a stationary computer.

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Evaporators and Freeze DryersCentrifugal evaporation is used for solvent removal from a sample. This is a useful technique for sample concentration or sample drying. Many centrifugal evaporators are modular with a central vacuum pump for generating low pressure. Useful features of evaporators or vacuum ovens include minimal solvent bumping, solvent resistance, computer control, temperature regulation and benchtop design.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.VaccinesAntibioticsAntibiotics are substances that kill or inhibit the growth of microorganisms, such as bacteria and fungi. They are essential in the treatment of infections and in preventing disease spread. Explore antibiotics research and diagnostic tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Sample StoragePreserving clinical trial samples to the highest standards is a critical component in maximizing the value of present day and future clinical research. Specialized storage and transportation of these tissue, blood and serum samples reduces the risk of them being damaged or lost.

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