Which Impeller Is Right for Your Cell Line? A Guide to Impeller Selection for Stirred-Tank Bioreactors

31 Jan 2014

This application note describes six commonly used fermentor and bioreactor impellers, explain how they work, and identify which may perform best for culturing certain animal, insect, plant, yeast, and bacterial cell lines.

Eppendorf New Brunswick™ BioFlo®/CelliGen® 510

Eppendorf

BioFlo 510 Fermentors and CelliGen 510 Bioreactors are intermediate systems ideal for pilot to small scale production processes. The modular design features a wide variety of standard options allowing this system to be flexible enough to meet most process requirements.   Eppendorf New Brunswick™ BioFlo®/CelliGen® 510 Working volumes: 10.75 L to 32.0 L Applications: Laboratory and pilot scale fermentation of aerobic and anaerobic bacteria, yeasts, and fungi; Laboratory and pilot scale cell culture of mammalian, insect, and human cell lines; Special applications such as stem cell culture, vaccine, monoclonal antibody, or biofuel/biopolymer production; Suitable for batch, fed batch, and continuous processes

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Eppendorf New Brunswick™ BioFlo® Pro

Eppendorf

BioFlo Pro Fermentors are modular systems designed for quick delivery, dependable operation and system flexibility, all at an affordable price. Pro systems utilize industry-standard components for dependable operation, and an Allen Bradley® CompactLogix™ programmable-logic controller (PLC) for easy integration into any production facility. The modular design enables multiple options to be added, removed, or changed at any time to meet your various process requirements. Fermentors available in 120, 240, 400,  & 1200 liter sizes. BioFlo® Pro Working Volumes: 45 L to 120 L 68 L to 240 L 103 L to 400 L 375 L to 1200 L Applications: Pilot and large scale fermentation of aerobic and anaerobic bacteria, yeasts, and fungi; Special applications such as vaccine or biofuel/biopolymer production; Suitable for batch, fed batch, and continuous processes

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.
Which Impeller Is Right for Your Cell Line? A Guide to Impeller Selection for Stirred-Tank Bioreactors