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Validation of the Method for Determination of Pesticide Residues by Gas Chromatography – Triple-Stage Quadrupole Mass Spectrometry

20 Nov 2015

This application note reports on in-house validation results and assessment of performance parameters of a complete multi-residue pesticide analysis method employing QuEChERS sample preparation kits, sample measurement by the newly developed Thermo Scientific™ TSQ™ 8000 Pesticide Analyzer system and rapid data analysis by Thermo Scientific™ TraceFinder™ software.

Thermo Scientific™ TRACE™ 1300 Series GC System

Thermo Fisher Scientific

The Thermo Scientific TRACE 1300 Series GC offers the most versatile gas chromatograph platform in the market, with unique "instant connect" modularity for ground-breaking ease of use and performance, setting a new era in GC technology.The Thermo Scientific TRACE 1300 Series GC is the ideal budget-conscious investment for the basic routine laboratory when lower operator expertise requires ease of use with minimal instrument interaction. Its simplified user-interface is also ideal for 24/7 operations that require single-button start/stop/maintenance local interactions while maintaining full programmability through the networked control software.Interchangeable modules free your laboratory from the challenges and constraints of the past. Remove the complexity and eliminate the need for specialized service assistance or new system requirements with modular injectors and detectors.Thermo Scientific Trace 1300 Series GC Features: Analyze dirtier matrices with minimum cleanup using the system's robust injector technology Analyze trace concentrations with smaller injection amounts and minimum preconcentration results using enhanced detector sensitivity and micro-volume technology Protect system components and reduce run time and maintenance using optional backflush capabilities Shorten sample cycle times using low thermal mass injectors and detectors and fast oven technology Automate your entire workflow—from pipetting to injection—using a full range of sample handling options Streamline and speed up data analysis using Thermo Scientific™ Dionex™ Chromeleon™ Chromatography Data System (CDS) software Expands easily from single-channel to multi-injector/detector GC configurations Reduces training and startup time with simplified installation, plug-in components, minimal local control and intuitive Chromeleon software Minimizes downtime with easy-access, tool-free modules Reduces operational costs by allowing use of standard consumables Saves energy with low thermal mass and quick start-up Minimizes sample and solvent consumption with micro-volume sample capability Modular design lets you easily reconfigure to meet changing requirements

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GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.QuEChERSThe QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) method is a streamlined approach that is used to extract multi-residue target compounds from food samples. It is most commonly used by analytical chemists studying pesticide residues in food.PesticidesPesticides are used to protect crops from diseases, pests and unwanted plants. They are classed as persistent organic pollutants (POPs) and can be harmful to humans. The Environmental Protection Agency (EPA) currently regulates the use of pesticides in the USA. Method ValidationMethod validation is the process used to prove that the analytical procedure used for a particular test is capable of providing suitable data.