ResourceLife Sciences
Validation of a Multiple Compound Addition Assay for hERG ion channel on the IonWorks Barracuda™ Automated Patch Clamp System
14 Aug 2012In this study, a multiple compound addition assay for hERG channel was validated by Molecular Devices. Compared to previously reported cross-plate assay, this “within-well” method examines cumulative concentration-response in a similar manner to manual patch clamp, with unparalleled throughput (4,6000 data points/hour) and comparable pharmacology...
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ElectrophysiologyElectrophysiology is the study of biological voltage changes, from a single ion channel through to a whole organ scale. Voltages can be measured using patch clamping, automated workstations, electrophysiology rigs or cell based assays. Specific cell lines, manipulators and microinjectors are also available for electrophysiology research.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.Within-WellHER2