SelectScience
Join Free
Accelerating Science
ResourceForensics

Using UPLC-MS/MS for the Determination of cTHC in Preserved Oral Fluid

Waters
13 Nov 2017

The requirement to analyse drugs at low levels in oral fluid has become an important requirement for many forensic laboratories around the world. Cannabis is one of the most widely used illicit substances and analysis of cTHC in saliva can indicate active cannabis consumption. This application note demonstrates how the Xevo TQ-S can be applied with the right sensitivity for such analyses.

Related products

Request Quote for All Products

CORTECS® Columns

Waters

Unleash the power of your laboratory's instrumentation. CORTECS® 1.6 µm and 2.7 µm solid-core columns deliver new levels of performance. CORTECS Columns are available in both reversed-phase and HILIC options, giving you the flexibility and power to develop methods for challenging separations even faster. With different particle characteristics and innovative charged surface modifications, CORTECS Columns are suitable for use in a wide variety of applications. CORTECS Columns offer particle sizes ideal for HPLC, UHPLC, and UPLC platforms, assuring a simple, seamless method transfer with consistent results across different particle sizes and column configurations. CORTECS 1.6 µm and 2.7 µm solid-core columns are suitable for use in a wide variety of applications. CORTECS Columns offer particle sizes ideal for HPLC, UHPLC, and UPLC platforms, assuring a simple, seamless method transfer with consistent results across different particle sizes and column configurations.

(14)

Links

WatersCompany website

Tags

UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Evidence Collection and AnalysisEvidence Collection and Analysis is the retrieval and subsequent investigation into criminal evidence obtained from a crime scene. Forensic genetic instruments, kits and reagents enable the analysis of evidence collected  at the crime scene. Reagents and kits for presumptive analysis for body fluids such as blood, saliva and semen in addition to drugs and narcotics test kits are used for CSI. Fingerprinting equipment, forensic light sources, casting kits and equipment for collecting recoverable materials can be found in the directory.Toxicology / Drugs of Abuse TestingToxicology and Drugs of Abuse Testing is the investigation into toxic and illegal substances found at the scene of a crime or from a suspect and / or victim associated with a scene of a crime. Analyzers, immunoassays and drugs of abuse test kits and presumptive test kits are an essential aspect of toxicology investigation.Drugs of AbuseA drug of abuse is a drug that has been taken for non-medical purposes. Such drugs can have mind-altering effects, with some causing dependence and addiction.CannabinoidsCannabinoids are compounds found in cannabis that have therapeutic effects, such as pain relief, anti-inflammatory properties, and potential neuroprotective benefits. Research into cannabinoids is growing, particularly in the fields of pain management, neurological diseases, and cancer treatments. Browse our peer-reviewed product directory to find the best cannabinoid research tools, compare products, check reviews, and get pricing directly from manufacturers.Toxicology ScreeningCannabis

Related resources

Using UPLC-MS/MS for the Determination of cTHC in Preserved Oral Fluid