ResourceLife Sciences
Using Qlucore Omics Explorer for Interpreting Leukemia Proteomics Data
27 Feb 2019Steven Kornblau, a Professor of Medicine in the Department of Leukemia & Department of Stem Cell Transplantation and Cellular Therapy at UT MD Anderson Cancer Center in Houston, Texas, US, uses proteomics – the large-scale study of proteins – in the fight against leukemia. The approach that he and his colleagues take is to look simultaneously at hundreds of proteins to define patterns of protein activation in acute myeloid leukemia (AML) and identify proteins whose function are key to the survival of leukemic cells.
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ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.LeukemiaProtein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.
