Using Isocratic Preparative Liquid Chromatography as a Quick First-Step Purification for Natural Product Isolation

Waters offers scalable prep systems, from the AutoPurification™ System for high-throughput fraction collection from hundreds of samples, to simple low-pressure mixing systems for purifying a few samples a day. Take the complexity out of purification with our versatile solutions that are capable of purifying micrograms to multiple grams, in a single system that can be configured to automatically process hundreds of samples. Key features include: •Robust and reliable systems improve your ability to manage increasing workload demands, including unattended instrument operation. •Flexible configurations enable easy scale-up from analytical to preparative chromatography. •Software that simplifies fraction collection — FractionLynx™ Application Manager automates the collection of detected fractions, tracks samples and fractions, and then presents the data in an easy-to-view format. •Easy-to-upgrade systems help you bring the latest technologies to your lab.

The Waters® MV-10 ASFE™ System is the first supercritical fluid extraction (SFE) system offering accelerated, multi-vessel sample extraction, resulting in a faster, greener, more selective alternative for analyte extractions from a wide variety of sample matrices. Whether your workflow requires enriching target analytes for analytical purposes, stripping unwanted material from a product, or collecting valuable essential oils from natural products, the MV-10 ASFE System is the most efficient extraction tool available. This system allows you to: •  Extract samples from up to 10 extraction vessels in a semi-automated fashion •  Accelerate throughput •  Lower operating costs compared to traditional hydrocarbon-based solvent extraction systems. •  Use a green alternative to normal phase solvents, supercritical CO2, which is non-toxic, non-flammable, and environmentally compatible. System features: •  Uses environmentally friendly CO2 instead of toxic organic solvents •  Improved extraction efficiency •  Better selectivity •  Increased speed •  Higher yield •  Reduced operating costs •  ChromScope™ Software makes routine analysis, reporting, and fraction collection easy with an intuitive user-friendly interface

XBridge Columns include a selection of 10 general-purpose and application-specific sorbents that cover a wide range of particles sizes for analytical and preparative HPLC applications.   XBridge Column users can quickly develop robust methods using mobile phases throughout the entire pH range of 1-12. XBridge OBD™ Preparative Column users, benefit from high pH and temperature stability to provide increased mass loading for basic compounds.   Robust HPLC methods Seamless HPLC to UPLC® method transfer Preparative scaling for product isolation High pH stability Long lifetime and high reliability Maximum method development flexibility High chemical resistance