Unleashing High-Throughput Reaction Screening the Unchained Way

A successful high-throughput approach to reaction screening requires rational and systematic exploration of a broad set of variables to achieve optimization expeditiously. There are many types of potential variables that can be screened. Even with the aid of high-throughput screening tools, chances are that it’s still unlikely to screen all the possible combinations of reaction variables a process chemist desires. A well-planned high-throughput approach enables scientists to more clearly see the “big picture”, quickly abandon disadvantaged routes and rapidly pinpoint advantageous and impactful conditions to focus on.