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Ultra-trace detection of PFAS in drinking water to meet new US EPA interim health advisory levels

11 Jun 2023

In this application note, Waters discusses per- and polyfluoroalkyl substances (PFAS), which are synthetic chemicals known for their stability and diverse structures. PFAS are used in various industries and consumer products, such as non-stick coatings and cosmetics. These chemicals are persistent, toxic, and accumulate in humans, animals, and the environment. PFAS can be found in contaminated drinking water, leading to negative impacts on human health. Detection of PFAS is becoming more challenging due to stricter regulatory limits. This application note focuses on achieving stringent PFAS limits using solid-phase extraction and analytical instruments from Waters.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Water AnalysisAnalytical methods used to test the purity of drinking water include determining the level of contaminants abides to the level set by the Environmental Protection Agency (EPA).Drinking Water AnalysisAnalytical methods used to test the purity of drinking water include determining the level of contaminants abides to the level set by the Environmental Protection Agency (EPA).
Ultra-trace detection of PFAS in drinking water to meet new US EPA interim health advisory levels