ResourceForensics

Ultra-Fast Forensic Toxicological Screening and Quantitation under 3 Minutes using SCIEX X500R QTOF System and SCIEX OS 1.0 Software

9 Jul 2017

There has been increasing use of high resolution and accurate mass LC-MS/MS systems for drug screening in forensic toxicological settings. This technical note, presents an ultra-fast forensic toxicological screening method using the new SCIEX X500R QTOF system and SCIEX OS 1.0 software. The LC runtime of this method is 2.5 minutes. Two different non-targeted data acquisition methods were used and compared, both of which yielded data that can be analyzed retrospectively.

X500R QTOF system

SCIEX

Made just for you, the X500R QTOF system is the first robust, high-performance high resolution MS system designed for routine use. The simple, balanced hardware design combined with the SCIEX OS software user interface makes the system easy to learn, and the robust performance ensures you get the right results quickly, reliably, and with maximum uptime for all your routine testing applications.   Features: Simplicity in hardware and software design for ease of operation, regardless of technician's skill set. Robustness delivered for analysis of complex samples with the Turbo V ionization source. Balanced across key criteria to deliver performance without compromise. Superior instrument uptime with fast and efficient maintenance. Stability through long runs with automated calibration. The sleek, compact design requires little lab space.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.Drugs of AbuseA drug of abuse is a drug that has been taken for non-medical purposes. Such drugs can have mind-altering effects, with some causing dependence and addiction.Drug TestingIt is essential to test the efficacy and toxicity of drugs at every stage of their development to ensure that a pharmaceutical product is fit for purpose and safe for use before reaching the stage of mass production and distribution.Forensic InvestigationForensic investigation is a diverse collection of scientific techniques and methods for the identification and characterization of chemicals relating to crime scene investigations.Drug Discovery & Development Screening