Transcreener® ADP2 TR-FRET Red Assay: Implementation on Tecan’s Infinite® multimode reader series

28 Feb 2014

The Transcreener ADP2 TR-FRET Red Assay is intended for the detection of ADP production by any kinase or
ATPase, and has been developed specifically for high throughput screening applications. The study described in this application note tests the Infinite F200 PRO, Infinite F500 and Infinite M1000 PRO multimode readers for their capacity to measure the Transcreener ADP2 TR-FRET Red Assay.

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Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.
Transcreener® ADP2 TR-FRET Red Assay: Implementation on Tecan’s Infinite® multimode reader series