ResourceGeneral Lab

Titer Determination in Volumetric Karl Fischer Titration

22 Sept 2016

This Application Bulletin provides information on the titer determination in Karl Fischer titration. It contains information on the types of water standards suitable for a titer determination as well as the correct handling of those standards.

901 Titrando for Karl Fischer Titration

Metrohm AG

901 Titrando - The Karl Fischer Titrando for the modern titration laboratory Thanks to its modular concept the Titrando System can be optimally adapted to any application. It meets the requirements of FDA Regulation 21 CFR Part 11. Profit from its intelligence and multiple communication options (USB, RS 232C, Remote)!In addition to the Karl Fischer mode (KFT), this high-end titrator also includes the SET mode, which means that titrations can be carried out to a predefined endpoint. "ITrode ready": The high-resolution, galvanically separated measuring interface - now also with additional digital measuring input for intelligent electrodes «iTrodes» - means that it is also possible to make high-precision pH measurements Transparent operation – thanks to specially adapted dialogs, the Titrando accelerates method development and simplifies routine operation. The large color screen of the Touch Control informs you about the instrument condition and offers uniquely comfortable operator guidance. For operation via a PC the appearance is exactly the same. Numerous worked-out methods and titration examples make familiarization easier. Method templates and calculation formula templates are available for developing your own methods. Extended titration and evaluation parameters open up new applications. More intelligence: The Data Chip of the Dosing Unit contains all important titrant data. Thanks to the sophisticated Liquid Handling, automatic reagent exchange is now also possible in volumetric KF titration. The 901 Titrando works with Dosing Units, which are ideal for handling KF reagents. Parallel titration – a Titrando can work with two titration cells at the same time (requires tiamo).

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Optrode Sensor for Titration

Metrohm AG

Sensor for titration with photometric endpoint recognition. Eight wave lengths: 470, 502, 520, 574, 590, 610, 640 and 660 nm 100% solvent-resistant due to glass shaft Compact and space-saving Very easy to clean Easy to change the wave lengths Both new and existing titration systems can be furnished with the optrode. The power supply is provided directly through the USB interface of a Metrohm instrument (Titrino plus, Ti-Touch, Titrando, USB sample changer). With older models without a USB interface, the power supply can also be provided by means of an optional USB power supply unit.

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Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.Robotic InstrumentsRobotic instruments can be used for high-throughput automation of many lab processes. Such processes use instruments for assays like cell based assays and ELISA, for sample preparation like shakers, centrifuges and incubators, and for analysis such as sequencing and western blot analyzers. Useful features of robotic instruments include speed, reproducibility, barcode readers, software and automation.Robotic WorkstationsRobotic workstations are automated platforms enabling the user to perform high-throughput, multi-application processes, from sample preparation tasks such as PCR set-up, DNA purification and NGS library preparation, to integrated sample prep and analysis workstations. Automation makes processes consistent, fast, precise and fully walk-away. Find the best robotic workstations in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.TitrationTitration is an analytical technique for determining substance concentration in a solution. For titration consider a manual or automated system, volumetric or coulometric reagent addition and indication by a potentiometer, spectrometer, turbidometer or by the Karl Fischer method. Other features of titration to consider include burettes, reagents, concentration range, reaction time and autosamplers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.Water Content AnalysisWater content analysis is crucial for determining the moisture levels in food, pharmaceuticals, chemicals, and other materials. Accurate measurement ensures product quality and shelf-life. Explore water content analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Sample ProcessingSample processing is required to prepare samples prior to analysis. Technologies used for sample processing include homogenizers, grinders, mills and mixers.
Titer Determination in Volumetric Karl Fischer Titration