Through-Container Identity Verification of Polysorbates with the Agilent RapID Raman System
4 Mar 2019Polysorbates are often packaged in a sealed, oxygen-free environment to prevent degradation. Amber glass bottles are common containers for polysorbates, often used in large numbers, making identification difficult and time-consuming. Manufacturers of polysorbates typically make different grades, so reliable identity verification is essential to mitigate mistakes in supply. This Application Note describes how the Agilent RapID Raman system can unambiguously verify the identity of the four common pharmaceutical grades of polysorbates through unopened amber glass bottles.
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RapID - Portable Raw Material ID Verification
Agilent TechnologiesThe RapID Raman system is the next generation in raw material testing for pharmaceutical GMP quality control. RapID is a portable Raman spectrometer that uses Agilent’s spatially offset Raman spectroscopy (SORS) technology to extend high-throughput spectroscopic analysis through clear packaging to nontransparent and colored containers. This unique capability makes RapID ideally suited to noninvasive raw material identity verification.