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The use of Microflow UHPLC as a Way to Reduce Solvent Usage in Pesticide Screening of Food Samples by LC/MS/MS

13 Jun 2012

Traditionally in pesticide screening food samples are prepared using generic extraction procedures, like QuEChERS and then analyzed by LC/MS/MS or GC/MS/MS. This poster presents new data using Microflow LC with a LC/MS/MS method developed on a system utilizing the Scheduled MRM™ algorithm in combination with fast polarity switching and acquisition of MS/MS spectra for compound identification.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Solvent ReductionPesticidesPesticides are used to protect crops from diseases, pests and unwanted plants. They are classed as persistent organic pollutants (POPs) and can be harmful to humans. The Environmental Protection Agency (EPA) currently regulates the use of pesticides in the USA.
The use of Microflow UHPLC as a Way to Reduce Solvent Usage in Pesticide Screening of Food Samples by LC/MS/MS