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The Quantitation and Identification of Artificial Sweeteners in Food and Drink by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
7 Jun 2012The method described in this application note, shows how LC-MS/MS can be used to simultaneously detect and confirm the presence of several artificial sweeteners. The method is both quicker than conventional non LC-MS/MS methods and more sensitive. This has meant that these compounds can be detected in samples below ingredient levels using a simple dilute and shoot approach.
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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Artificial Sweeteners