The Importance of Enrichment Assay Choice and Optimization for Confident Variant Detection

29 Nov 2013

This white paper investigates the main strategies employed to optimize target enrichment for next generation sequencing (NGS) assays, assisting researchers to make informed decisions when designing studies.

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Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Target-Enrichment
The Importance of Enrichment Assay Choice and Optimization for Confident Variant Detection