The Effects of LC Particle Choice on Column Performance
15 Dec 2014Superficially porous particles (commonly referred to as SPP or “core-shell” particles) have proven to provide fast and efficient LC separations. These particles feature a solid, impermeable core enveloped by a thin, porous layer of silica that offers significantly higher efficiency and sensitivity than traditional fully porous particles (FPP). In this application note, performance of Raptor™ 5 μm SPP LC column is compared to traditional 3 and 5 μm FPP LC columns. We will demonstrate how faster, more efficient analyses can be attained with greater sensitivity and reduced system pressure by switching from fully porous particles to superficially porous particles—without changing instrumentation.
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Raptor™ C18 LC Columns (USP L1)
Restek Corp.Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation.