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The BIOSTAT® ORB Large Scale Shaken Single Use Bioreactor for the Biopharmaceutical Industry: Use and Applications

19 Dec 2014

Sartorius has recently introduced a novel technology in the field of single use bioreactors. The BIOSTAT® ORB is a single use bioreactor based on a proven shaker agitation principle and can offer a cost-efficient alternative to other single use technologies existing in the market. This application note describes the principles of this new technology as well as instructions on setting up its process parameters. Finally, cultivation data will be presented confirming the BIOSTAT® ORB to be a worthy alternative to existing technologies.

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Shakers, Stirrers and MixersShakers, stirrers and mixers are used for mixing liquids and solids for laboratory applications. There is a wide range of laboratory mixing equipment available, including magnetic stirrers, orbital shakers, linear shakers, microplate shakers, 3D gyratory rockers, rotators & vortexers. Additional platforms and clamps can also be attached to shakers to increase capacity. Find the best shakers, stirrers and mixers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.ManufacturingManufacturing is the production of merchandise for use or sale using labor and machines, tools, chemical and biological processing, or formulation.
The BIOSTAT® ORB Large Scale Shaken Single Use Bioreactor for the Biopharmaceutical Industry: Use and Applications