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The art behind good filtration: How to get the best out of filtration

SelectScience

This application eBook provides detailed advice to help pharmaceutical laboratories avoid common setbacks and produce accurate results. Explore this expert guide on drug dissolution testing, and discover how to choose the best filter for your workflows.

9 Dec 2022

Drug dissolution testing measures the rate an active pharmaceutical ingredient (API) is released from a solid dosage form, as it dissolves. Pharmaceutical laboratories routinely use drug dissolution during quality control testing to assess the consistency of batches of tablets, pills, and capsules before market release.

This application eBook provides detailed advice to help pharmaceutical laboratories avoid common setbacks and produce accurate and reliable results more efficiently. Explore this expert guide on drug dissolution testing, and discover how to choose the best filter for your workflows.

This eBook will also cover:

  • The extensive portfolio of Whatman™ filters from Cytiva
  • How to effectively remove impurities from your sample
  • How opting for the right filter can save time and reduce costs
  • The basics of dissolution testing

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Whatman Roby Automated Filter Validation Kit, 25 mm

Cytiva

Cytiva's Roby filter validation kit offers five different Roby automated syringe filters, along with a filter validation protocol and filter selection aid. Tubes of 25 filters are ready for loading into tablet tester systems.

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Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.FiltrationFiltration and microfiltration are used to separate solids, particulates or large molecules from fluids (liquid or gases) in order to purify the filtrate. Explore a range of filter formats, including filter paper, plates and membranes for your separation needs. While larger particulates may be separated by gravity filtration, smaller particulates may require additional force for timely separation. Microfiltration equipment includes vacuum filters, as well as positive pressure, crossflow and centrifugal filtration devices. Find the best filtration products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.Active PharmaceuticalsThe Active Pharmaceutical Ingredient (API) of a drug is the component that causes the direct effect of the product. The remaining inactive components are known as excipients.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.Drug DevelopmentDrug development refers to the process of bringing a new drug to market.

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