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Texture: Transdermal Delivery Systems

6 May 2013

Transdermal Drug Delivery Systems (TDDS) are a fundamental part of novel drug delivery systems. This application note describes use of the Brookfield CT3 Texture Analyzer to quantify the tack performance of a transdermal delivery patch. This is measured as the adhesive force required to break contact between the probe surface and adhesive of the patch using a ball probe.

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Mechanical TestingMechanical testing explores the elastic and inelastic nature of a material when force is applied. A mechanical test shows whether a material is suitable for its intended application by measuring hardness, tensile strength, elongation, elasticity, and fatigue limit.Texture AnalysisDrug DosageDosage is the size or frequency of the administration of a drug. Determination of the dosage of a drug is critical in pharmaceutical development to ensure the optimum balance between efficacy and toxicity.