Targeted MRM screening of U-13C lipid yeast extracts for robust lipidomics applications

24 Nov 2025

Fatty acids (FAs) and lipids are important biological compounds that are essential to the regulation and control of cellular functions (e.g., membrane structure, signal transduction, apoptosis) and metabolic pathways (e.g., fatty acid oxidation, ketone body synthesis, lipolysis). These biomolecules are also functionally important to an organism’s energy production and storage.

In this application note, Cambridge Isotope Laboratories qualifies a condensed panel of stable isotope-labeled FAs/lipids in U-13C crude lipid yeast extracts on robust, high-throughput, analytical platforms.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. LipidsLipids are a diverse group of organic compounds that are insoluble in water, including fats, oils, and hormones. They are critical for cellular structure and energy storage. Explore lipid analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Yeast