Targeted LC-SRM/MS quantification of mammalian synaptic proteins with Mouse Express Brain Tissue, a new isotopically labeled proteome standard

24 Nov 2025

In this study, discover how protein standards, generated from stable isotope labeling in mammals (SILAM) with L-lysine·2HCl (13C6, 99%) (CLM-2247-H) allow for multiplexed targeted quantitative analysis of protein trafficking in brain tissue without the costly and untimely synthesis of individual peptide or protein standards.

Links

Tags

Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.NeuroscienceNeuroscience research investigates the neurological mechanisms underlying behavior, neurodegenerative diseases, and other brain conditions. Learn about the innovative technologies for bioimaging, electrophysiology, cell culture, chromatography and other techniques used in this field.Protein Quantification
Targeted LC-SRM/MS quantification of mammalian synaptic proteins with Mouse Express Brain Tissue, a new isotopically labeled proteome standard