Taking the fear out of iPS cell line development

In this application note, Cell Microsystems shows how to dramatically improve the efficiency and success of iPSC cloning, while decreasing time, expense, and effort. Here, Cell Microsystems shows that the ability of the CellRaft Array to provide flask-like culture conditions while maintaining spatial separation of single cells greatly improved iPSC viability and monoclonal colony formation. In addition, a single consumable can screen thousands of iPSCs, decreasing the time required for cell line generation and therapeutic discovery. Together, CellRaft Array technology and the automated imagining and isolation capabilities of the CellRaft AIR System can increase the utility of iPSCs by collapsing complicated iPSC maintenance and cell line development workflows.